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Osteoporosis Health Centre
Treatment

Osteoporosis and Drug Therapy

Drug therapy is only one aspect of treatment for osteoporosis. Other factors to prevent further bone loss, increase bone mass and prevent fractures include: Each aspect of managing osteoporosis plays a role. A combined approach gives the best results.

In Canada, several drug therapies have been officially approved for the prevention and/or treatment of osteoporosis. These include:

Hormone Replacement Therapy (HRT)
Approved for Prevention

  • estrogen with or without progesterone

Bisphosphonates
Approved for both Prevention and Treatment

  • etidronate, available as Didronel® or with calcium supplements as Didrocal®
  • alendronate, available as Fosamax®
  • risedronate, available as ActonelŽ
Selective Estrogen Receptor Modulators (SERM)
Approved for both Prevention and Treatment
  • raloxifene, available as Evista®

Calcitonin
Approved for Treatment

  • calcitonin nasal spray available as Miacalcin®

Other medications are prescribed only for certain groups of people with osteoporosis:

  • calcitriol
  • low-dose oral contraceptives
  • testosterone
  • sodium fluoride
Research studies are looking into the effectiveness of other conventional medicines. These include:
  • other bisphosphonates
  • other SERMS
  • growth hormones
  • nitrates
  • vitamin K

Parathyroid Hormone (PTH) Injections

  • has recently been approved in the United States and is under review by the Canadian Health Protection Branch as a medication for the treatment of osteoporosis

There is also growing patient interest in the possible effectiveness of alternative and naturopathic remedies such as:

  • natural progesterone cream
  • compounded estrogen formulations (eg. BI-EST, TRI-EST)
  • phytoestrogens
  • ipriflavone
Scientific studies have not yet proven the effectiveness of alternate and naturopathic remedies.

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Last Updated: May 2005

 
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