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Osteoporosis Health Centre
Medical Description

Two classes of osteoporosis

Osteoporosis can be classed as either primary or secondary.

Primary osteoporosis

There are two different types of primary osteoporosis.

Type 1 - Post-menopausal osteoporosis
Type 1 usually occurs between the ages of 50 to 70, largely because of estrogen loss at menopause. It mainly affects trabecular bone - the spongy looking bone on the inside of the vertebrae. Much of the spine is made up of trabecular bone, which looks like a honeycomb. It is very susceptible to the effects of estrogen deficiency at menopause.

Type 2 - Age-related osteoporosis
Type 2 is related directly to the aging process. It usually occurs in people older than 70 years. It affects both trabecular and cortical bone. Twenty percent of bone is trabecular bone and 80 percent is cortical bone. Eighty percent of bone turnover occurs in the smaller amount of trabecular bone.

Secondary osteoporosis

Secondary osteoporosis can have many causes, including:
  • diseases that affect the endocrine system, such as hyperparathyroidism or hyperthyroidism
  • gastrointestinal (digestive) tract diseases - Crohns disease (due to poor gut absorption of calcium and vitamin D)
  • alcoholism
  • liver disease
  • premature menopause
  • amenorrhea or loss of periods due to an eating disorder (low estrogen levels)
  • a vitamin D deficiency
  • time spent in bed because of illness (non-weight bearing activity)
  • poor nutrition
Sometimes, it is not the condition that causes osteoporosis, but the drug used to treat other health problems. For example:
  • phenytoin (e.g. Dilantin - used for treatment of epilepsy)
  • corticosteroids (e.g. Prednisone, inhaled steroids for asthma)
  • drugs given to transplant patients (e.g. Heparin, Cyclosporin, corticosteroids).
If you have an illness that needs medication, ask your doctor or pharmacist if either the disease or medication has any effect on your bone mass. Sometimes, taking the lowest dose possible to treat a condition can lesson the effect on bones.

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Last Updated: January 2009

 
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